Safety in Assisted Reproductive Technologies: Insights from Gene Expression Studies During Preimplantation Development

نویسندگان

  • Daniela Bebbere
  • Luisa Bogliolo
  • Federica Ariu
  • Irma Rosati
  • Sergio Ledda
چکیده

The mammalian oocyte and embryo display considerable plasticity. Even in sub-optimal conditions, as in vitro environment may be certainly considered, the oocyte is able to mature, face fertilization and develop first into an embryo and finally to a live offspring. Such ability has encouraged, over the decades, the development of numerous in vitro assisted reproductive technologies (ART) in several species, included human. Nowadays, more than 30 years after its inception, human ART are routinely and successfully applied to solve fertility problems, which affect ~ 15% of reproductive age couples and have significant medical, social and financial implications.

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تاریخ انتشار 2017